Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279503 | 0.93 | KMT2A (0.57) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7827940 | 0.88 | KMT2A (0.72) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7827937 | 0.88 | KMT2A (0.72) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL27543049 | 0.84 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7829189 | 0.83 | KMT2A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7829186 | 0.83 | KMT2A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22279354 | 0.82 | KMT2A (0.62) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7813951 | 0.80 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7822412 | 0.80 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7822408 | 0.80 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166460-B2 | α-amino acrylate microbicide, and preparation method therefor and uses thereof | NANKAI UNIVERSITY (CN) | 2021-11-09 | — | — | US | disclosed |
| US-20200236935-A1 | a-Amino Acrylate microbicide, and preparation method therefor and uses thereof | UNIV NANKAI (CN) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200236935-A1 | a-Amino Acrylate microbicide, and preparation method therefor and uses thereof | AASDHPPT, ACE, ADA | KMT2A 2990/4885MEN1 1923/4885ALDH1A1 322/4885 |
| US-11166460-B2 | α-amino acrylate microbicide, and preparation method therefor and uses thereof | ACE, AASDHPPT, DDT | KMT2A 3353/4885MEN1 1949/4885ALDH1A1 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.