SCHEMBL22279611

SCHEMBL22279611

O=C(CI)Oc1ccc(C(=O)O)c(OC(=O)CI)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.58
▸ ELANE P08246 4/20 0.49
▸ ALDH1A1 P00352 6/20 0.45
▸ MAPT P10636 2/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ ESR1 P03372 2/20 0.40
▸ ESR2 Q92731 1/20 0.40
▸ HSD17B10 Q99714 5/20 0.39
▸ HPGD P15428 4/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ USP2 O75604 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ ITGB3 P05106 1/20 0.35
▸ ITGA2B P08514 1/20 0.35
▸ HMGB1 P09429 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ GGT1 P19440 1/20 0.35
▸ PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22279455 0.82 SMN1; SMN2 (0.49) KDM4EELANEALDH1A1MAPTHPGD
SCHEMBL22279458 0.82 RARB (0.43) KDM4EALDH1A1
SCHEMBL8442036 0.80 ESR1 (0.40) KDM4EALDH1A1ESR1ESR2HSD17B10
SCHEMBL6690405 0.77 KDM4E (0.61) KDM4EALDH1A1MAPTMAPK1ESR1
SCHEMBL22279609 0.77 CA12 (0.33) KDM4EELANEALDH1A1MAPK1HSD17B10
SCHEMBL22279612 0.74 KDM4E (0.59) KDM4EELANEALDH1A1MAPTMAPK1
SCHEMBL5603081 0.74 KDM4E (1.00) KDM4EELANEALDH1A1MAPTMAPK1
SCHEMBL11704461 0.74 KDM4E (0.64) KDM4EELANEALDH1A1MAPTMAPK1
SCHEMBL22279459 0.73 KDM4E (0.36) KDM4EALDH1A1MAPTESR1HSD17B10
SCHEMBL6691150 0.73 HSD17B10 (0.52) ELANEMAPK1ESR1HSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11720020-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-08 — — US disclosed
US-11720020-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-08 — — US disclosed
US-11586110-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-02-21 — — US disclosed
US-11415887-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-08-16 — — US disclosed
US-20210048746-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-18 — — US disclosed
US-20210033971-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 — — US disclosed
US-20210033969-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 — — US disclosed
US-20210033970-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 — — US disclosed
US-20200272048-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-27 — — US disclosed
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS INSR, HNRNPU, HNRNPR KDM4E 2213/4885ELANE 2178/4885ALDH1A1 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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