SCHEMBL22279459

SCHEMBL22279459

O=C(CI)Oc1ccc(C(=O)O)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ RECQL P46063 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ MRGPRX4 Q96LA9 6/20 0.35
▸ ASPH Q12797 1/20 0.35
▸ KDM8 Q8N371 1/20 0.35
▸ CFD P00746 2/20 0.34
▸ HSD17B10 Q99714 4/20 0.33
▸ HPGD P15428 3/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.33
▸ USP2 O75604 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ CES2 O00748 1/20 0.32
▸ CES1 P23141 1/20 0.32
▸ ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25946842 0.83 CFD (0.37) KDM4EMEN1RECQLKMT2AMRGPRX4
SCHEMBL22279463 0.78 ALDH1A1 (0.36) KDM4EMRGPRX4ASPHKDM8CFD
SCHEMBL6698411 0.77 CFD (0.56) KDM4EASPHKDM8CFDHSD17B10
SCHEMBL22374145 0.77 CES2 (0.33) ALOX15CES2CES1
SCHEMBL22279485 0.75 CDC25B (0.48) KDM4EMEN1RECQLKMT2AHSD17B10
SCHEMBL25946844 0.74 KDM4E (0.38) KDM4EMEN1RECQLKMT2AMRGPRX4
SCHEMBL22279453 0.74 KDM4E (0.37) KDM4EMRGPRX4ASPHKDM8CFD
SCHEMBL6690405 0.74 KDM4E (0.61) KDM4EMEN1RECQLKMT2AHSD17B10
SCHEMBL704976 0.74 TSHR (0.50) KDM4EMEN1KMT2AMRGPRX4ASPH
SCHEMBL22279611 0.73 KDM4E (0.58) KDM4EMEN1RECQLKMT2ACFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 — — US disclosed
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 — — US disclosed
US-11720020-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-08 — — US disclosed
US-11586110-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-02-21 — — US disclosed
US-20210048746-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-18 — — US disclosed
US-20210033970-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 — — US disclosed
US-20210033969-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 — — US disclosed
US-20210033971-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 — — US disclosed
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200241414-A1 RESIST COMPOSITION AND PATTERNING PROCESS INSR, HNRNPU, HNRNPR KDM4E 2213/4885MEN1 2251/4885RECQL 3314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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