SCHEMBL22279743

SCHEMBL22279743

CC(C)(C)c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12794176 0.92 CYP1A2 (0.31) CYP1A2CYP3A4CYP2C9HIF1A
SCHEMBL28427396 0.89 CYP1A2 (0.30) CYP1A2CYP3A4CYP2C9HIF1A
SCHEMBL12705765 0.76
SCHEMBL5587548 0.76 ALDH1A1 (0.37) CYP1A2CYP3A4CYP2C9HIF1A
SCHEMBL14131044 0.74 CYP3A4 (0.47) CYP1A2CYP3A4HIF1A
SCHEMBL12265914 0.74
SCHEMBL5800199 0.72 CYP1A2 (0.33) CYP1A2CYP3A4CYP2C9HIF1A
SCHEMBL8220621 0.70 POLB (0.31)
SCHEMBL14305276 0.70
SCHEMBL19651525 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912822-B2 Process of manufacturing polyols DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-27 US disclosed
US-11912822-B2 Process of manufacturing polyols DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-27 US disclosed
US-20230312803-A1 POLYURETHANE COMPOSITION DOW GLOBAL TECHNOLOGIES LLC 2023-10-05 US disclosed
US-20230312803-A1 POLYURETHANE COMPOSITION DOW GLOBAL TECHNOLOGIES LLC 2023-10-05 US disclosed
US-20220033565-A1 POLYURETHANES AND METHOD FOR MAKING POLYURETHANES DOW GLOBAL TECHNOLOGIES LLC 2022-02-03 US disclosed
US-20210284789-A1 HIGH DIELECTRIC BREAKDOWN POLYMERS; COMPOSITIONS; METHODS OF MAKING; AND USE THEREOF UNIVERSITY OF CONNECTICUT 2021-09-16 US disclosed
US-20200354383-A1 PROCESS OF MANUFACTURING POLYOLS DOW GLOBAL TECHNOLOGIES LLC 2020-11-12 US disclosed
US-20200277436-A1 PROCESS OF MANUFACTURING SURFACTANTS AND LUBRICANTS DOW GLOBAL TECHNOLOGIES LLC 2020-09-03 US disclosed
US-20200239619-A1 PROCESS OF MANUFACTURING POLYOLS DOW GLOBAL TECHNOLOGIES LLC 2020-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912822-B2 Process of manufacturing polyols MRPL21, RER1, PCBP1 CYP1A2 909/4885CYP3A4 1762/4885CYP2C9 1817/4885
US-20200354383-A1 PROCESS OF MANUFACTURING POLYOLS MRPL21, RER1, PCBP1 CYP1A2 909/4885CYP3A4 1762/4885CYP2C9 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.