SCHEMBL5587548

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23079376	0.82	HPGD (0.40)	ALDH1A1HPGDTSHRHSD17B10MEN1
	SCHEMBL22279743	0.76	CYP1A2 (0.31)	CYP2C9HIF1ACYP1A2CYP3A4
	SCHEMBL12794176	0.76	CYP1A2 (0.31)	CYP2C9HIF1ACYP1A2CYP3A4
	SCHEMBL19193446	0.76	CA2 (0.36)	ALDH1A1LMNAMAPTCYP2C9CYP1A2
	SCHEMBL28427396	0.73	CYP1A2 (0.30)	CYP2C9HIF1ACYP1A2CYP3A4
	SCHEMBL2220776	0.73	CA2 (0.35)	ALDH1A1LMNAMAPTCYP1A2CA2
	SCHEMBL6232540	0.73	HSD17B10 (0.44)	ALDH1A1HPGDTSHRHSD17B10MEN1
	SCHEMBL112121	0.73	TSHR (0.50)	ALDH1A1HPGDTSHRHSD17B10MEN1
	SCHEMBL122888	0.72	CA2 (0.38)	ALDH1A1TSHRLMNAMAPTCYP2C9
	SCHEMBL11699334	0.71	SMN1; SMN2 (0.50)	ALDH1A1HPGDTSHRHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.