Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562453 | 0.86 | KDM4E (0.54) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL2227307 | 0.84 | KDM4E (0.60) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL12517342 | 0.84 | KDM4E (0.60) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL15330012 | 0.82 | KDM4E (0.73) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL2228132 | 0.82 | KDM4E (0.56) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL3964259 | 0.82 | MAPT (0.46) | KDM4EMAPTALDH1A1GAAL3MBTL1 | |
| Water SCHEMBL2228975 | 0.81 | KDM4E (0.54) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL2227475 | 0.81 | MAPT (0.52) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL2227626 | 0.77 | ALDH1A1 (0.74) | KDM4EMAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL15331447 | 0.77 | TBK1 (0.57) | KDM4EMAPTNPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |