Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227992 | 0.81 | KDM4E (0.56) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3964259 | 0.81 | MAPT (0.46) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2287837 | 0.80 | KAT2B (0.46) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2227870 | 0.78 | HPGD (0.44) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2229604 | 0.78 | GAA (0.40) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL12517358 | 0.78 | GBA1 (0.51) | KDM4EALDH1A1LMNAL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL2229679 | 0.77 | GBA1 (0.50) | KDM4EALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL2229253 | 0.77 | RAB9A (0.47) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL2228484 | 0.76 | MAPT (0.44) | MAPTKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3953197 | 0.75 | ENPP2 (0.47) | MAPTKDM4EALDH1A1ENPP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | claimed |
| WO-2011089457-A1 | NOVEL MEDICINAL COMPOUNDS | URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2011-07-28 | — | — | WO | disclosed |