Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280269 | 1.00 | RAB9A (0.71) | RAB9ANPC1TLR9TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL193439 | 0.99 | RAB9A (0.69) | RAB9ANPC1TLR9TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL193440 | 0.99 | RAB9A (0.69) | RAB9ANPC1TLR9TLR8TLR7 | |
| SCHEMBL22280323 | 0.92 | NPC1 (0.66) | RAB9ANPC1TLR9TLR8TLR7 | |
| SCHEMBL22280324 | 0.92 | NPC1 (0.66) | RAB9ANPC1TLR9TLR8TLR7 | |
| SCHEMBL193730 | 0.87 | GRM5 (0.55) | RAB9ANPC1TLR9TLR8TLR7 | |
| SCHEMBL192832 | 0.87 | GRM5 (0.55) | RAB9ANPC1TLR9TLR8TLR7 | |
| SCHEMBL192560 | 0.87 | GRM5 (0.55) | RAB9ANPC1TLR9TLR8TLR7 | |
| SCHEMBL193626 | 0.86 | S1PR1 (0.53) | RAB9ANPC1L3MBTL1CASP3SENP7 | |
| SCHEMBL193523 | 0.86 | ALDH1A1 (0.54) | RAB9ANPC1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154431-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | LYNCH KEVIN R (US) | 2020-07-30 | — | — | WO | disclosed |