Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14637938 | 0.84 | FAAH (0.55) | POLBALDH1A1NPC1FAAHSMN1; SMN2 | |
| SCHEMBL22280602 | 0.81 | SMN1; SMN2 (0.59) | TP53POLBHPGDLMNAALDH1A1 | |
| SCHEMBL22280625 | 0.78 | LMNA (0.49) | TP53POLBHPGDLMNAALDH1A1 | |
| SCHEMBL5186144 | 0.77 | CYP1A2 (0.51) | TP53HPGDLMNAALDH1A1NPC1 | |
| SCHEMBL14638292 | 0.77 | FAAH (0.53) | TP53HPGDLMNAALDH1A1NPC1 | |
| SCHEMBL14636700 | 0.76 | CDK8 (0.50) | FAAH | |
| SCHEMBL15194995 | 0.75 | LMNA (0.72) | LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL111664 | 0.74 | LMNA (0.75) | POLBHPGDLMNAALDH1A1NPC1 | |
| SCHEMBL22582336 | 0.74 | LMNA (0.65) | LMNAALDH1A1NPC1 | |
| SCHEMBL6057368 | 0.73 | LMNA (0.64) | TP53POLBHPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |