Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280423 | 0.85 | FAAH (0.43) | FAAHSLC6A4SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL19923176 | 0.77 | SLC6A3 (0.59) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22280594 | 0.76 | EDNRA (0.45) | SLC6A4SLC6A3PDK2 | |
| SCHEMBL30956571 | 0.73 | SLC6A4 (0.41) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30956592 | 0.73 | MRGPRX4 (0.41) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30956550 | 0.72 | SLC6A4 (0.40) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30956563 | 0.72 | KMO (0.48) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1401560 | 0.72 | TSHR (0.57) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19484320 | 0.71 | FAAH (0.55) | FAAHSLC6A4SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL13824070 | 0.71 | SLC6A3 (0.53) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |
| WO-2020153431-A1 | ESTER COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |