Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.66 |
| ▸ | ACE | P12821 | 3/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258772 | 1.00 | PREP (0.66) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL2228388 | 0.96 | PREP (0.71) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL11764594 | 0.96 | PREP (0.71) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL11761001 | 0.93 | PREP (0.67) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL13471059 | 0.93 | PREP (0.67) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL11760983 | 0.93 | PREP (0.67) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL1189713 | 0.90 | FKBP1A (0.63) | PREPACEFKBP1AALDH1A1 | |
| SCHEMBL2082597 | 0.88 | PREP (0.69) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL9518270 | 0.87 | PREP (0.68) | PREPACEFKBP1AALDH1A1KMT2A | |
| SCHEMBL11033242 | 0.87 | PREP (0.68) | PREPACEFKBP1AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217226-B1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-20130045962-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2013-02-21 | — | — | US | disclosed |
| US-20090306066-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045962-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, DPEP1, DHPS | PREP 4/4885ACE 415/4885FKBP1A 1059/4885 |
| US-20090306066-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, DHPS, PADI3 | PREP 9/4885ACE 1278/4885FKBP1A 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.