Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2698404 | 0.85 | ALDH1A1 (0.48) | CA1CA2KDM4EABCG2GAA | |
| SCHEMBL39734 | 0.83 | CA1 (0.60) | RXRACA1CA2KDM4ECA12 | |
| SCHEMBL22396440 | 0.82 | KMT2A (0.49) | RXRAKDM4ELMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL19118500 | 0.81 | CA1 (0.58) | RXRACA1CA2KDM4ECA12 | |
| Hydrochloric Acid SCHEMBL3361588 | 0.81 | CA1 (0.58) | RXRACA1CA2KDM4ECA12 | |
| 3,5-Dimethoxybenzoic Acid SCHEMBL503889 | 0.79 | RXRA (0.64) | RXRACA1CA2KDM4ECA12 | |
| SCHEMBL22396432 | 0.79 | ALOX15 (0.45) | LMNAGAAMEN1KMT2ANPC1 | |
| SCHEMBL56890 | 0.78 | KDM4E (0.55) | RXRACA1CA2KDM4ECA12 | |
| SCHEMBL25508690 | 0.77 | RXRA (0.58) | RXRACA1CA2KDM4ECA12 | |
| 3,5-Dimethoxybenzoic Acid SCHEMBL20592058 | 0.77 | RXRA (0.62) | RXRACA1CA2KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088181-A9 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
| EP-2533783-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |