SCHEMBL22288256

SCHEMBL22288256

O=C(ONCl)c1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
L3MBTL1 Q9Y468 5/20 0.52
LMNA P02545 2/20 0.52
NAPRT Q6XQN6 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
ALDH1A1 P00352 4/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
TLR7 Q9NYK1 2/20 0.49
THRB P10828 1/20 0.48
GAA P10253 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
PKM P14618 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698244 0.81 ALDH1A1 (0.55) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL30679670 0.81 ALDH1A1 (0.55) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL27796737 0.79 CES2 (0.50) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL5673163 0.79 CES2 (0.50) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL30166417 0.79 KDM4E (0.68) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL1424253 0.79 CES2 (0.59) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL247011 0.79 KDM4E (0.68) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL29576494 0.79 KDM4E (0.68) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL31633615 0.78 CES2 (0.64) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL1228223 0.78 CES2 (0.64) CES2CES1L3MBTL1LMNANAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021139482-A1 CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED IMINO ARYL COMPOUND, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2021-07-15 WO disclosed
WO-2021043114-A1 SUBSTITUTED THIADIAZINONE DIOXIDE AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND APPLICATION THEREFOR 青岛清原化合物有限公司 2021-03-11 WO disclosed
WO-2020156106-A1 HETEROCYCLIC ARYL FORMAMIDES OR SALT THEREOF, PREPARATION METHOD, WEEDING COMPOSITION, AND APPLICATION 青岛清原化合物有限公司 2020-08-06 WO disclosed