Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22315707 | 0.91 | POLB (0.38) | HTR2CHTR6RAB9ASMN1; SMN2HPGD | |
| SCHEMBL22316240 | 0.89 | MEN1 (0.40) | HTR2CHTR6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL22315702 | 0.87 | LTA4H (0.46) | CYP1A2SMN1; SMN2ALDH1A1MAPTMAOB | |
| SCHEMBL22315704 | 0.86 | HSD17B10 (0.40) | HTR2CHTR6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL22316238 | 0.84 | ELANE (0.33) | HTR2CHTR6NPC1RAB9ATNF | |
| SCHEMBL22315699 | 0.84 | HTR2C (0.34) | HTR2CHTR6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL22316469 | 0.84 | SLC6A4 (0.38) | HTR2CHTR6NPC1RAB9ATNF | |
| SCHEMBL22316935 | 0.84 | NPC1 (0.39) | HTR2CHTR6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL576746 | 0.82 | HSD17B10 (0.52) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22288787 | 0.81 | MAOA (0.49) | CYP3A4NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917909-A1 | DISULPHIDE COMPOUNDS | Neem Biotech Limited (GB) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020157463-A1 | DISULPHIDE COMPOUNDS | NEEM BIOTECH LIMITED (GB) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020157463-A1 | DISULPHIDE COMPOUNDS | NEEM BIOTECH LIMITED (GB) | 2020-08-06 | — | — | WO | disclosed |