Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.44 |
| ▸ | CDC25B | P30305 | 8/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.44 |
| ▸ | TACR2 | P21452 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26658241 | 0.80 | PTPN1 (0.45) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL15972562 | 0.74 | HTR1A (0.49) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL3898367 | 0.74 | NT5E (0.54) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL15968116 | 0.74 | NT5E (0.54) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL12127979 | 0.74 | HTR1A (0.49) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL3898371 | 0.74 | NT5E (0.54) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL17766609 | 0.74 | NT5E (0.54) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL18681815 | 0.74 | HTR1A (0.49) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL24146782 | 0.73 | NT5E (0.49) | NT5EHTR1APTPN1CDC25BPTPN2 | |
| SCHEMBL19189070 | 0.73 | HTR1A (0.51) | NT5EHTR1APTPN1CDC25BPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365608-A1 | ANTIVIRAL NUCLEOSIDES AND DERIVATIVES THEREOF | JANSSEN BIOPHARMA, LLC | 2023-11-16 | — | — | US | disclosed |
| EP-3917922-A1 | ANTIVIRAL NUCLEOSIDES AND DERIVATIVES THEREOF | Janssen BioPharma, Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020157694-A9 | ANTIVIRAL NUCLEOSIDES AND DERIVATIVES THEREOF | Janssen Biopharma, Inc. (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2020157694-A1 | ANTIVIRAL NUCLEOSIDES AND DERIVATIVES THEREOF | Janssen Biopharma, Inc. (US) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365608-A1 | ANTIVIRAL NUCLEOSIDES AND DERIVATIVES THEREOF | PNP, NUDT1, ADAR | NT5E 34/4885HTR1A 2321/4885PTPN1 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.