Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | FES | P07332 | 1/20 | 0.68 |
| ▸ | RET | P07949 | 1/20 | 0.68 |
| ▸ | MARK3 | P27448 | 1/20 | 0.68 |
| ▸ | TYK2 | P29597 | 1/20 | 0.68 |
| ▸ | FLT4 | P35916 | 1/20 | 0.68 |
| ▸ | SYK | P43405 | 1/20 | 0.68 |
| ▸ | CLK2 | P49760 | 1/20 | 0.68 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130703 | 0.90 | FES (0.81) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL29460250 | 0.90 | FES (0.81) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL29684017 | 0.85 | NAMPT (0.76) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL30559826 | 0.84 | RECQL (0.77) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL255574 | 0.83 | FES (0.68) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL29550751 | 0.83 | RECQL (1.00) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL163993 | 0.83 | RECQL (1.00) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL14323610 | 0.82 | FLT4 (0.97) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL18327711 | 0.82 | FES (0.91) | RECQLFESRETMARK3TYK2 | |
| SCHEMBL10403403 | 0.81 | RECQL (0.72) | RECQLFESRETMARK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113348017-A | Hydrazide compound and kinase inhibitor | 日产化学株式会社 | 2021-09-03 | — | — | CN | disclosed |
| WO-2020158841-A1 | HYDRAZIDE COMPOUND AND KINASE INHIBITOR | 日産化学株式会社 | 2020-08-06 | — | — | WO | disclosed |