SCHEMBL29550751

SCHEMBL29550751

NC(=O)NCc1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 1.00
MAPT P10636 1/20 0.64
ALDH1A1 P00352 2/20 0.64
FES P07332 1/20 0.62
RET P07949 1/20 0.62
MARK3 P27448 1/20 0.62
TYK2 P29597 1/20 0.62
FLT4 P35916 1/20 0.62
SYK P43405 1/20 0.62
CLK2 P49760 1/20 0.62
CLK4 Q9HAZ1 1/20 0.62
GAA P10253 2/20 0.61
CYP3A4 P08684 2/20 0.60
USP2 O75604 2/20 0.60
CYP1A2 P05177 2/20 0.60
NPSR1 Q6W5P4 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
PKM P14618 1/20 0.60
KMT2A Q03164 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163993 1.00 RECQL (1.00) RECQLMAPTALDH1A1FESRET
SCHEMBL30559826 0.87 RECQL (0.77) RECQLMAPTALDH1A1FESRET
SCHEMBL25779421 0.86 RECQL (0.76) RECQLMAPTALDH1A1FESRET
SCHEMBL1704281 0.86 RECQL (0.75) RECQLMAPTALDH1A1FESRET
SCHEMBL29460250 0.85 FES (0.81) RECQLMAPTALDH1A1FESRET
SCHEMBL9130703 0.85 FES (0.81) RECQLMAPTALDH1A1FESRET
SCHEMBL2424556 0.84 RECQL (0.72) RECQLMAPTALDH1A1FESRET
SCHEMBL10403403 0.84 RECQL (0.72) RECQLMAPTALDH1A1FESRET
SCHEMBL27823198 0.83 RECQL (0.70) RECQLSMN1; SMN2L3MBTL1LMNA
SCHEMBL1274303 0.83 RECQL (0.71) RECQLMAPTALDH1A1FESRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161201-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2025-05-22 US claimed
EP-4479146-A1 COSMETIC COMPOSITION The Boots Company PLC (GB) 2024-12-25 EP claimed
CN-119110720-A Cosmetic composition 布茨公司 2024-12-10 CN claimed
CN-118994104-A Compound serving as PARP-NAMPT double-target inhibitor and application thereof 天津市医药科学研究所(天津市医药与健康研究中心) 2024-11-22 CN claimed
WO-2023156070-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2023-08-24 WO claimed
CN-115109049-A Triazine compound containing aryl urea structure and application thereof 江西科技师范大学 2022-09-27 CN claimed
US-20250304576-A1 IKK INHIBITORS CANCER RESEARCH TECH LTD (GB) 2025-10-02 US disclosed
US-12240862-B2 Inhibitors of peptidylarginine deiminases GILEAD SCIENCES, INC. (US) 2025-03-04 US disclosed
CN-119300805-A Skin care compositions and methods of use 高露洁-棕榄公司 2025-01-10 CN disclosed
EP-4479021-A1 COSMETIC COMPOSITION CONTAINING RETINOID, EXTRACT OF CENTELLA ASIATICA AND A DIPEPTIDE The Boots Company PLC (GB) 2024-12-25 EP disclosed
CN-119110720-A Cosmetic composition 布茨公司 2024-12-10 CN disclosed
CN-119072299-A Cosmetic composition containing retinoid, centella asiatica extract and dipeptide 布茨公司 2024-12-03 CN disclosed
CN-118994104-A Compound serving as PARP-NAMPT double-target inhibitor and application thereof 天津市医药科学研究所(天津市医药与健康研究中心) 2024-11-22 CN disclosed
CN-115109049-B Triazine compound containing aryl urea structure and application thereof 江西科技师范大学 2023-08-15 CN disclosed
CN-115735024-A Copper electroplating bath 德国艾托特克有限两合公司 2023-03-03 CN disclosed
CN-115286617-A Protac compound for targeted degradation of NAMPT and application thereof 中国人民解放军海军军医大学 2022-11-04 CN disclosed
CN-115109049-A Triazine compound containing aryl urea structure and application thereof 江西科技师范大学 2022-09-27 CN disclosed
WO-2022165254-A1 KITS FOR DERMAL CARE CHEMISTRYRX (US) 2022-08-04 WO disclosed
CN-108883260-B Skin care applicator 宝洁公司 2022-04-29 CN disclosed
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2022-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304576-A1 IKK INHIBITORS NFKBIA, IKBKE, IKBKB RECQL 380/4885MAPT 1448/4885ALDH1A1 4083/4885
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNT, NQO1 RECQL 2720/4885MAPT 694/4885ALDH1A1 511/4885
US-20250161201-A1 COSMETIC COMPOSITION CYP19A1, SHBG, HSD17B11 RECQL 1290/4885MAPT 2895/4885ALDH1A1 2131/4885
US-12240862-B2 Inhibitors of peptidylarginine deiminases PADI4, PADI2, PADI1 RECQL 884/4885MAPT 3578/4885ALDH1A1 2537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.