Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132121 | 0.85 | TDP1 (0.44) | TDP1POLBAPEX1HTTMCL1 | |
| SCHEMBL20110987 | 0.83 | TDP1 (0.42) | TDP1POLBAPEX1HTTMCL1 | |
| SCHEMBL24245300 | 0.82 | POLB (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL16351917 | 0.80 | TDP1 (0.41) | TDP1POLBAPEX1HTTRARB | |
| SCHEMBL19826125 | 0.78 | TDP1 (0.38) | TDP1POLBAPEX1HTTRARB | |
| SCHEMBL17678822 | 0.78 | CFD (0.36) | TDP1POLBAPEX1HTTPDE4A | |
| SCHEMBL16351873 | 0.77 | TDP1 (0.38) | TDP1POLBAPEX1HTTPDE4A | |
| SCHEMBL15713257 | 0.77 | THRB (0.47) | TDP1TSHRCA1CA2L3MBTL1 | |
| SCHEMBL17209081 | 0.77 | THRB (0.47) | TDP1TSHRCA1CA2L3MBTL1 | |
| SCHEMBL544688 | 0.77 | TDP1 (0.56) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10729820-B2 | Methods and processes for application of drug delivery polymeric coatings | ARISTE MEDICAL, LLC (US) | 2020-08-04 | — | — | US | disclosed |