SCHEMBL2229415

SCHEMBL2229415

[CH2]CC(CC(=O)O)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.45
ESR2 Q92731 8/20 0.45
CYP3A4 P08684 4/20 0.44
ALDH1A1 P00352 2/20 0.44
CA2 P00918 2/20 0.41
CAMK2A Q9UQM7 1/20 0.41
MIF P14174 1/20 0.40
HIF1A Q16665 2/20 0.37
CYP2C19 P33261 1/20 0.37
TYR P14679 2/20 0.35
LMNA P02545 1/20 0.35
AR P10275 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
HTR6 P50406 1/20 0.35
ESRRG P62508 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2233016 0.85 ESR1 (0.46) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL5522093 0.79 ESR1 (0.52) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL2232385 0.79 ESR1 (0.53) ESR1ESR2AR
SCHEMBL51339 0.78 ESR1 (0.69) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL4239236 0.77 KIF11 (0.46) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL4235812 0.72 ESR1 (0.67) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL4214180 0.72 CA2 (0.48) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL11510565 0.72 ESR2 (0.56) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL5990790 0.72 ESR1 (0.56) ESR1ESR2CYP3A4ALDH1A1CA2
SCHEMBL8727572 0.72 ESR1 (0.47) ESR1ESR2CYP3A4ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023153481-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-08-17 WO disclosed
EP-4227107-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-08-16 EP disclosed
EP-3680110-A1 THERMOSENSITIVE RECORDING MATERIAL Ricoh Company, Ltd. (JP) 2020-07-15 EP disclosed
EP-3219506-B1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH CO LTD (JP) 2019-11-06 EP disclosed
CN-110402201-A Linerless thermosensitive recording body package body RICOH CO LTD 2019-11-01 CN disclosed
EP-3287292-B1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH CO LTD (JP) 2019-06-19 EP disclosed
US-20190001727-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH COMPANY, LTD. (JP) 2019-01-03 US disclosed
US-10118427-B2 Thermosensitive recording materials containing chelating agents RICOH COMPANY, LTD. (JP) 2018-11-06 US disclosed
EP-3287292-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS Ricoh Company, Ltd. (JP) 2018-02-28 EP disclosed
US-20170267008-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH COMPANY, LTD. (JP) 2017-09-21 US disclosed
EP-3219506-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS Ricoh Company, Ltd. (JP) 2017-09-20 EP disclosed
EP-2716466-B1 THERMAL RECORDING MATERIAL CONTAINING STILBENE DISULPHONIC ACID FLUORESCENT WHITENING AGENT RICOH IND FRANCE SAS (FR) 2016-09-14 EP disclosed
EP-2163393-B1 Thermosensitive recording material RICOH CO LTD (JP) 2016-03-02 EP disclosed
EP-2722190-B1 Optimized undercoat for thermal recording material RICOH IND FRANCE SAS (FR) 2015-12-16 EP disclosed
EP-2722190-A1 Optimized undercoat for thermal recording material Ricoh Industrie France SAS (FR) 2014-04-23 EP disclosed
EP-2345541-B1 Thermosensitive recording material and image recording method RICOH CO LTD (JP) 2012-08-29 EP disclosed
EP-2345541-A2 Thermosensitive recording material and image recording method Ricoh Company, Ltd. (JP) 2011-07-20 EP disclosed
EP-2163393-A1 Thermosensitive recording material Ricoh Co., Ltd. (JP) 2010-03-17 EP disclosed