SCHEMBL2232385

SCHEMBL2232385

[CH2]CC(CC(=O)O)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 19/20 0.53
ESR2 Q92731 6/20 0.53
AR P10275 3/20 0.53
VDR P11473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4238030 0.79 ESR1 (0.55) ESR1ESR2ARVDR
SCHEMBL6535262 0.79 ESR1 (0.55) ESR1ESR2ARVDR
SCHEMBL29690460 0.79 ESR1 (0.55) ESR1ESR2ARVDR
SCHEMBL2229415 0.79 ESR1 (0.45) ESR1ESR2AR
SCHEMBL11346568 0.72 ESR1 (0.66) ESR1ESR2ARVDR
SCHEMBL1325327 0.72 ESR1 (0.49) ESR1ESR2AR
SCHEMBL28415532 0.72 ESR1 (0.62) ESR1ESR2AR
SCHEMBL18249371 0.71 ALDH1A1 (0.41) ESR1ESR2
SCHEMBL837374 0.70 ESR1 (1.00) ESR1ESR2ARVDR
SCHEMBL30058620 0.70 ESR1 (1.00) ESR1ESR2ARVDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US claimed
WO-2023153481-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-08-17 WO disclosed
EP-4227107-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-08-16 EP disclosed
EP-3680110-A1 THERMOSENSITIVE RECORDING MATERIAL Ricoh Company, Ltd. (JP) 2020-07-15 EP disclosed
CN-110402201-A Linerless thermosensitive recording body package body RICOH CO LTD 2019-11-01 CN disclosed
US-20190001727-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH COMPANY, LTD. (JP) 2019-01-03 US disclosed
US-10118427-B2 Thermosensitive recording materials containing chelating agents RICOH COMPANY, LTD. (JP) 2018-11-06 US disclosed
US-20170267008-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH COMPANY, LTD. (JP) 2017-09-21 US disclosed
EP-2716466-B1 THERMAL RECORDING MATERIAL CONTAINING STILBENE DISULPHONIC ACID FLUORESCENT WHITENING AGENT RICOH IND FRANCE SAS (FR) 2016-09-14 EP disclosed
EP-2163393-B1 Thermosensitive recording material RICOH CO LTD (JP) 2016-03-02 EP disclosed
EP-2722190-B1 Optimized undercoat for thermal recording material RICOH IND FRANCE SAS (FR) 2015-12-16 EP disclosed
EP-2722190-A1 Optimized undercoat for thermal recording material Ricoh Industrie France SAS (FR) 2014-04-23 EP disclosed
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-2345541-B1 Thermosensitive recording material and image recording method RICOH CO LTD (JP) 2012-08-29 EP disclosed
EP-2230090-B1 Method and apparatus for producing thermosensitive recording material RICOH CO LTD (JP) 2012-08-29 EP disclosed
EP-2345541-A2 Thermosensitive recording material and image recording method Ricoh Company, Ltd. (JP) 2011-07-20 EP disclosed
EP-2230090-A1 Method and apparatus for producing thermosensitive recording material Ricoh Company, Ltd. (JP) 2010-09-22 EP disclosed
EP-2163393-A1 Thermosensitive recording material Ricoh Co., Ltd. (JP) 2010-03-17 EP disclosed
EP-1972459-B1 Heat-sensitive recording material RICOH KK (JP) 2009-11-04 EP disclosed
EP-1972459-A1 Heat-sensitive recording material Ricoh Company, Ltd. (JP) 2008-09-24 EP disclosed