Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 13/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007693 | 0.78 | TLR7 (0.49) | TLR7TLR8ADORA2ALMNAPOLB | |
| SCHEMBL1703454 | 0.77 | TLR7 (0.52) | TLR7TLR8ADORA2ALMNAPOLB | |
| SCHEMBL1010420 | 0.75 | LMNA (0.44) | TLR7TLR8ADORA2ALMNAPOLB | |
| SCHEMBL14694195 | 0.72 | TLR7 (0.40) | TLR7TLR8ADORA2ALMNAPOLB | |
| SCHEMBL14694192 | 0.72 | TLR7 (0.40) | TLR7TLR8ADORA2ALMNAPOLB | |
| SCHEMBL13868217 | 0.72 | NCF1 (0.47) | ADRA1DADRA1ANCF1 | |
| SCHEMBL1496311 | 0.72 | NCF1 (0.47) | ADRA1DADRA1ANCF1 | |
| SCHEMBL19272107 | 0.72 | NCF1 (0.47) | ADRA1DADRA1ANCF1 | |
| SCHEMBL14431011 | 0.72 | NCF1 (0.47) | ADRA1DADRA1ANCF1 | |
| SCHEMBL1062179 | 0.71 | BACE1 (0.49) | TLR7TLR8ADORA2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512478-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084549-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-07-14 | — | — | WO | disclosed |