SCHEMBL22294684

SCHEMBL22294684

C=C/C=C\CC/C=C\C=C/CC

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.39
PPARA Q07869 1/20 0.38
TSHR P16473 2/20 0.30
LSS P48449 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8775510 0.89 PPARA (0.42) TRPA1PPARATSHRLSSALDH1A1
SCHEMBL8775516 0.89 PPARA (0.42) TRPA1PPARATSHRLSSALDH1A1
SCHEMBL1760692 0.88
SCHEMBL22111 0.88
SCHEMBL22112 0.88
SCHEMBL9539568 0.87 ALDH1A1 (0.40) TRPA1PPARATSHRALDH1A1
SCHEMBL9539566 0.87 ALDH1A1 (0.40) TRPA1PPARATSHRALDH1A1
SCHEMBL23650044 0.85
Butadiene SCHEMBL4181280 0.85 TRPA1 (0.45) TRPA1
SCHEMBL11246643 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3440063-B1 AMINOTHIAZOLE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS INNOVATIVE MOLECULES GMBH (DE) 2020-08-05 EP disclosed