Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | DNM2 | P50570 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | SELL | P14151 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228181 | 0.86 | SELL (0.44) | ALOX5NAAASELLSELPKDM4E | |
| SCHEMBL2229568 | 0.73 | SELL (0.38) | ALOX5SELLSELPKDM4ERECQL | |
| SCHEMBL9143670 | 0.73 | NAAA (0.68) | ALOX5NAAAALDH1A1HPGDTSHR | |
| SCHEMBL22505247 | 0.70 | POLB (0.61) | ALOX5NAAAKDM4ERECQLALDH1A1 | |
| SCHEMBL30211623 | 0.70 | POLB (0.61) | ALOX5NAAAKDM4ERECQLALDH1A1 | |
| SCHEMBL2229534 | 0.70 | SELL (0.40) | ALOX5SELLSELPKDM4ERECQL | |
| SCHEMBL18285037 | 0.70 | ALOX5 (0.60) | ALOX5KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13952095 | 0.69 | ALOX5 (0.82) | ALOX5DNM2NAAAALDH1A1MAPT | |
| SCHEMBL25410705 | 0.68 | ALOX5 (0.50) | ALOX5DNM2SELLSELP | |
| SCHEMBL26936095 | 0.68 | ALOX5 (0.79) | ALOX5DNM2NAAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011085454-A1 | GP120 -BINDING BENZENE COMPOUNDS AND SACCHARIDE COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D (BE) | 2011-07-21 | — | — | WO | disclosed |