Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229548 | 0.86 | ALOX5 (0.44) | SELLSELPALOX5KDM4EALDH1A1 | |
| SCHEMBL2229568 | 0.79 | SELL (0.38) | SELLSELPALOX5KDM4EALDH1A1 | |
| SCHEMBL26296693 | 0.76 | SELL (0.56) | SELLSELPALOX5KDM4EALDH1A1 | |
| SCHEMBL2229534 | 0.75 | SELL (0.40) | SELLSELPALOX5KDM4EALDH1A1 | |
| SCHEMBL30736511 | 0.75 | KMT2A (0.62) | HPGDKMT2ANSD2L3MBTL1BCL2 | |
| SCHEMBL2233917 | 0.75 | KDM4E (0.52) | SELLSELPKDM4EALDH1A1MAPT | |
| SCHEMBL9143670 | 0.72 | NAAA (0.68) | ALOX5ALDH1A1HPGDNAAAL3MBTL1 | |
| SCHEMBL17748296 | 0.72 | LMNA (0.47) | ALOX5KDM4EMAPTRECQLHDAC1 | |
| SCHEMBL31099240 | 0.72 | SELL (0.55) | SELLSELPALOX5KDM4EMAPT | |
| SCHEMBL4213430 | 0.70 | ALDH1A1 (0.59) | SELLSELPALOX5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011085454-A1 | GP120 -BINDING BENZENE COMPOUNDS AND SACCHARIDE COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D (BE) | 2011-07-21 | — | — | WO | disclosed |