Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17570583 | 0.85 | PDE9A (0.39) | PDE9APDE1CKDM4EALDH1A1RXFP1 | |
| SCHEMBL21950752 | 0.77 | PDE9A (0.34) | PDE9APDE1CKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17570592 | 0.74 | MAOA (0.41) | PDE9APDE1CKDM4EALDH1A1RXFP1 | |
| SCHEMBL27018739 | 0.74 | PDE9A (0.39) | PDE9APDE1CKDM4EALDH1A1RXFP1 | |
| SCHEMBL16127590 | 0.73 | MAOA (0.38) | KDM4EALDH1A1RXFP1SMN1; SMN2 | |
| SCHEMBL20596319 | 0.72 | ALDH1A1 (0.45) | PDE9APDE1CADRA2AKDM4EALDH1A1 | |
| SCHEMBL23894163 | 0.72 | ADORA3 (0.30) | — | |
| SCHEMBL24624341 | 0.71 | PDE1C (0.43) | PDE9APDE1CADRA2AKDM4EALDH1A1 | |
| SCHEMBL24623399 | 0.71 | PDE1C (0.43) | PDE9APDE1CADRA2AKDM4EALDH1A1 | |
| SCHEMBL24623468 | 0.70 | ALDH1A1 (0.45) | PDE9APDE1CADRA2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375785-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-08-05 | — | — | EP | disclosed |