Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | CES1 | P23141 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28303524 | 0.98 | FAAH (0.49) | FAAHCES1SIGMAR1L3MBTL1MAOA | |
| SCHEMBL28037433 | 0.83 | FAAH (0.55) | FAAHCES1SIGMAR1MAOAMAPT | |
| SCHEMBL31038120 | 0.83 | FAAH (0.55) | FAAHCES1SIGMAR1MAOAMAPT | |
| SCHEMBL29449362 | 0.83 | ALDH1A1 (0.44) | CES1L3MBTL1 | |
| SCHEMBL9192045 | 0.81 | MAOA (0.52) | FAAHCES1SIGMAR1L3MBTL1MAOA | |
| SCHEMBL4742953 | 0.81 | MAOA (0.52) | SIGMAR1L3MBTL1MAOAMAOB | |
| SCHEMBL17288469 | 0.80 | FAAH (0.51) | FAAHCES1SIGMAR1MAOAMAPT | |
| SCHEMBL17288637 | 0.80 | FAAH (0.51) | FAAHCES1SIGMAR1MAOAMAPT | |
| SCHEMBL28882516 | 0.79 | FAAH (0.46) | FAAHCES1SIGMAR1L3MBTL1MAOA | |
| SCHEMBL23136877 | 0.79 | FAAH (0.44) | FAAHCES1SIGMAR1L3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426032-B1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-05 | — | — | EP | disclosed |