Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AMY2A | P04746 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 3/20 | 0.44 |
| ▸ | PYGB | P11216 | 1/20 | 0.43 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | GJA1 | P17302 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976778 | 0.89 | MEN1 (0.49) | MEN1KMT2ALGALS3LGALS8LGALS4 | |
| SCHEMBL21698210 | 0.87 | LGALS8 (0.53) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL23430833 | 0.87 | LGALS8 (0.53) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL21894588 | 0.87 | LGALS8 (0.53) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL23735640 | 0.87 | LGALS8 (0.53) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL23617758 | 0.87 | LGALS8 (0.53) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL22296782 | 0.87 | LGALS8 (0.53) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL16217741 | 0.87 | LGALS8 (0.53) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL19031176 | 0.84 | MEN1 (0.50) | MEN1KMT2AAMY2ALGALS3LGALS8 | |
| SCHEMBL23603194 | 0.82 | AMY1A (0.50) | MEN1KMT2AAMY2ALGALS3LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3690049-A1 | COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRESSION | Ionis Pharmaceuticals, Inc. (US) | 2020-08-05 | — | — | EP | disclosed |