Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21207933 | 0.87 | ALDH1A1 (0.36) | ALDH1A1BDKRB1HCRTR2TLR9TLR8 | |
| SCHEMBL29343516 | 0.85 | ALDH1A1 (0.35) | ALDH1A1BDKRB1HCRTR2TLR9TLR8 | |
| SCHEMBL25581265 | 0.80 | ALDH1A1 (0.42) | ALDH1A1BDKRB1GNAI3GNAO1GNAI1 | |
| SCHEMBL22875066 | 0.76 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1NPC1KDM4E | |
| SCHEMBL22006751 | 0.76 | NAAA (0.32) | — | |
| SCHEMBL20233673 | 0.72 | NPC1 (0.43) | ALDH1A1BDKRB1L3MBTL1NPC1KDM4E | |
| SCHEMBL20129213 | 0.72 | CYP2C19 (0.36) | — | |
| SCHEMBL824150 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HCRTR2NPC1 | |
| SCHEMBL14023006 | 0.72 | NPC1 (0.42) | ALDH1A1GNAI3GNAO1GNAI1L3MBTL1 | |
| SCHEMBL20233802 | 0.72 | KMT2A (0.36) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |
| EP-3689868-A1 | TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Arvinas Operations, Inc. (US) | 2020-08-05 | — | — | EP | disclosed |