Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21207933 | 0.87 | ALDH1A1 (0.36) | ALDH1A1BDKRB1GNAI3GNAO1GNAI1 | |
| SCHEMBL26381330 | 0.86 | — | — | |
| SCHEMBL21477198 | 0.86 | NPC1 (0.46) | ALDH1A1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL22297429 | 0.85 | ALDH1A1 (0.38) | ALDH1A1BDKRB1GNAI3GNAO1GNAI1 | |
| SCHEMBL25581265 | 0.80 | ALDH1A1 (0.42) | ALDH1A1BDKRB1GNAI3GNAO1GNAI1 | |
| SCHEMBL20233673 | 0.78 | NPC1 (0.43) | ALDH1A1BDKRB1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL22560667 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL22875066 | 0.76 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL23349991 | 0.76 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL18551613 | 0.75 | CES2 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |