Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213060 | 0.72 | MAPK1 (0.53) | MAPTP2RY1TAAR1ALDH1A1KDM4E | |
| SCHEMBL31069449 | 0.71 | ALDH1A1 (0.59) | ALOX5ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8528008 | 0.71 | MAPT (0.46) | MAPTALOX5ALDH1A1KDM4EHPGD | |
| SCHEMBL304891 | 0.71 | CXCR2 (0.54) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL16904081 | 0.70 | AMY1A (0.49) | MAPTALOX5TAAR1MIFALDH1A1 | |
| SCHEMBL1920752 | 0.69 | CXCR2 (0.52) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL3587772 | 0.68 | MAPT (0.53) | MAPTTAAR1MIFALDH1A1KDM4E | |
| SCHEMBL15688032 | 0.68 | MECP2 (0.51) | MAPTP2RY1POLBMEN1GAA | |
| SCHEMBL6374941 | 0.67 | MAPT (0.47) | MAPTP2RY1TAAR1MIFALDH1A1 | |
| SCHEMBL5959497 | 0.66 | GBA1 (0.51) | MAPTALDH1A1KDM4ETSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343287-A1 | New 2-aminothiadiazole derivatives | Almirall, S.A. (ES) | 2011-07-13 | — | — | EP | disclosed |