Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227755 | 0.86 | KMT2A (0.41) | KMT2AALDH1A1GAAMAPTLMNA | |
| SCHEMBL2229081 | 0.81 | MAPT (0.35) | KMT2AALDH1A1GAAMAPTLMNA | |
| SCHEMBL28794976 | 0.74 | GRM5 (0.35) | KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2227867 | 0.72 | BRD4 (0.43) | KMT2AALDH1A1GAAMAPTLMNA | |
| SCHEMBL2229020 | 0.70 | KMT2A (0.41) | KMT2AALDH1A1GAAMAPTLMNA | |
| SCHEMBL24611548 | 0.65 | KMT2A (0.40) | KMT2AALDH1A1GAAMAPTLMNA | |
| SCHEMBL6901376 | 0.65 | ALDH1A1 (0.44) | KMT2AALDH1A1GAAMAPT | |
| SCHEMBL20552309 | 0.63 | TSHR (0.49) | ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL9281088 | 0.61 | GAA (0.53) | KMT2AALDH1A1GAAMAPTLMNA | |
| SCHEMBL1548694 | 0.61 | ALDH1A1 (0.54) | KMT2AALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091346-A2 | POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2011-07-28 | — | — | WO | disclosed |