Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.53 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22302859 | 0.85 | ALDH1A1 (0.52) | MAPK14RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4622848 | 0.82 | CYP24A1 (0.58) | CYP24A1CYP27A1CYP26A1DRD2HTR2A | |
| SCHEMBL8921371 | 0.81 | CYP24A1 (0.54) | CYP24A1CYP27A1CYP26A1DRD2HTR2A | |
| SCHEMBL31522714 | 0.81 | DDB1 (0.56) | MAPK14RAB9ACYP19A1DDB1CRBN | |
| SCHEMBL28617274 | 0.81 | ACHE (0.52) | RAB9A | |
| SCHEMBL22302860 | 0.78 | RAB9A (0.48) | CYP24A1CYP26A1RAB9ACYP19A1NPC1 | |
| SCHEMBL5217220 | 0.78 | MAPK1 (0.53) | CYP24A1CYP27A1CYP26A1DRD2HTR2A | |
| SCHEMBL9131953 | 0.77 | MEN1 (0.52) | CYP24A1CYP27A1CYP26A1DRD2HTR2A | |
| SCHEMBL15291331 | 0.76 | CYP24A1 (0.52) | CYP24A1CYP27A1CYP26A1DRD2HTR2A | |
| SCHEMBL4548389 | 0.76 | CYP24A1 (0.55) | CYP24A1CYP27A1CYP26A1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020158870-A1 | PARKINSON'S DISEASE THERAPEUTIC | 学校法人慶應義塾 | 2020-08-06 | — | — | WO | disclosed |