Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230303 | 1.00 | NPC1 (0.38) | NPC1RAB9AAGTR1PKMKDM4E | |
| Hydrochloric Acid SCHEMBL3295936 | 0.97 | NPC1 (0.40) | NPC1RAB9AAGTR1PKMKDM4E | |
| Hydrochloric Acid SCHEMBL3295940 | 0.97 | NPC1 (0.40) | NPC1RAB9AAGTR1PKMKDM4E | |
| Hydrochloric Acid SCHEMBL14632794 | 0.97 | RAB9A (0.37) | NPC1RAB9AAGTR1PKMKDM4E | |
| SCHEMBL5352634 | 0.86 | PAX8 (0.32) | NPC1RAB9AAGTR1PKMKDM4E | |
| SCHEMBL6877976 | 0.86 | PAX8 (0.32) | NPC1RAB9AAGTR1PKMKDM4E | |
| SCHEMBL1685488 | 0.81 | KDM4E (0.34) | NPC1RAB9AAGTR1PKMKDM4E | |
| SCHEMBL1685486 | 0.81 | KDM4E (0.34) | NPC1RAB9AAGTR1PKMKDM4E | |
| SCHEMBL23457658 | 0.81 | ALDH1A1 (0.36) | NPC1RAB9AAGTR1KDM4ESMN1; SMN2 | |
| SCHEMBL23457659 | 0.81 | ALDH1A1 (0.36) | NPC1RAB9AAGTR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089000-A1 | PROCESS FOR THE PREPARATION OF ETHYLENE COPOLYMER COMPOSITIONS IN THE PRESENCE OF AN OLIGOMERIZATION CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2011-07-28 | — | — | WO | disclosed |
| EP-1943281-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | Basell Polyolefine GmbH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042252-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | BASELL POLYOLEFINE GMBH (DE) | 2007-04-19 | — | — | WO | disclosed |