Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239668 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KCNA5LMNAPOLBKMT2A | |
| SCHEMBL7995142 | 0.91 | ALDH1A1 (0.67) | ALDH1A1KCNA5POLBKMT2AGABBR2 | |
| SCHEMBL27396478 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KCNA5LMNAPOLBKMT2A | |
| SCHEMBL28354797 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBKMT2AGABBR2 | |
| SCHEMBL27323723 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KCNA5KMT2AGABBR2GABBR1 | |
| SCHEMBL12268202 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KCNA5POLBKMT2AGABBR2 | |
| SCHEMBL1811811 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KCNA5POLBKMT2AGABBR2 | |
| SCHEMBL1923824 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNAPOLBKMT2AGABBR2 | |
| SCHEMBL27653392 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBKMT2AGABBR2 | |
| SCHEMBL10285065 | 0.84 | ESR1 (0.51) | ALDH1A1LMNAFFAR1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053746-A1 | IL-17 LIGANDS AND USES THEREOF | DICE MOLECULES SV, INC. | 2023-02-23 | — | — | US | disclosed |
| US-20200247785-A1 | IL-17 Ligands And Uses Thereof | DICE MOLECULES SV, INC. | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230053746-A1 | IL-17 LIGANDS AND USES THEREOF | IL17A, IL2, IL15 | ALDH1A1 951/4885KCNA5 4786/4885LMNA 3817/4885 |
| US-20200247785-A1 | IL-17 Ligands And Uses Thereof | IL17A, IL2, IL15 | ALDH1A1 951/4885KCNA5 4786/4885LMNA 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.