Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 6/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424092 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KCNA5F2F10PRSS1 | |
| SCHEMBL28267935 | 0.88 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL7995142 | 0.88 | ALDH1A1 (0.67) | ALDH1A1KCNA5KMT2AFNTAFNTB | |
| SCHEMBL1811944 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KCNA5F2F10PRSS1 | |
| SCHEMBL28044957 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KCNA5F2F10PRSS1 | |
| SCHEMBL22303151 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KCNA5KMT2AGABBR2GABBR1 | |
| SCHEMBL7239668 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KCNA5KMT2AGABBR2GABBR1 | |
| SCHEMBL2719599 | 0.85 | F2 (0.61) | ALDH1A1F2F10PRSS1KMT2A | |
| SCHEMBL13715201 | 0.85 | ESR1 (0.54) | ALDH1A1F2F10PRSS1MAPT | |
| SCHEMBL13715340 | 0.85 | ESR1 (0.54) | ALDH1A1F2F10PRSS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046711-C | Unsaturated hydroxyalkyl quinoline carboxylic acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1999-11-24 | — | — | CN | disclosed |