SCHEMBL7239668

SCHEMBL7239668

CCC(CC(=O)OC)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
KCNA5 P22460 2/20 0.49
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
KMT2A Q03164 2/20 0.47
GABBR2 O75899 1/20 0.44
GABBR1 Q9UBS5 1/20 0.44
FFAR1 O14842 1/20 0.44
HPGD P15428 1/20 0.44
MAPT P10636 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ATM Q13315 1/20 0.44
MEN1 O00255 1/20 0.44
TSHR P16473 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
PKM P14618 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22303151 1.00 ALDH1A1 (0.57) ALDH1A1KCNA5LMNAPOLBKMT2A
SCHEMBL7995142 0.91 ALDH1A1 (0.67) ALDH1A1KCNA5POLBKMT2AGABBR2
SCHEMBL27396478 0.88 ALDH1A1 (0.50) ALDH1A1KCNA5LMNAPOLBKMT2A
SCHEMBL28354797 0.87 ALDH1A1 (0.48) ALDH1A1LMNAPOLBKMT2AGABBR2
SCHEMBL27323723 0.86 ALDH1A1 (0.55) ALDH1A1KCNA5KMT2AGABBR2GABBR1
SCHEMBL12268202 0.86 ALDH1A1 (0.61) ALDH1A1KCNA5POLBKMT2AGABBR2
SCHEMBL1811811 0.86 ALDH1A1 (0.61) ALDH1A1KCNA5POLBKMT2AGABBR2
SCHEMBL1923824 0.86 ALDH1A1 (0.47) ALDH1A1LMNAPOLBKMT2AGABBR2
SCHEMBL27653392 0.85 ALDH1A1 (0.54) ALDH1A1LMNAPOLBKMT2AGABBR2
SCHEMBL10285065 0.84 ESR1 (0.51) ALDH1A1LMNAFFAR1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414398-B Compound, active energy ray-curable composition, cured product thereof, printing ink, and ink for inkjet recording DIC株式会社 2019-04-05 CN disclosed
CN-106414398-A Compound, active energy ray-curable composition, cured product thereof, printing ink, and ink for inkjet recording DIC株式会社 2017-02-15 CN disclosed
CN-101006063-B Five-membered heterocycles useful as serine protease inhibitors. BRISTOL MYERS SQUIBB CO 2013-07-17 CN disclosed
CN-101006063-A Five-membered heterocycles useful as serine protease inhibitors. BRISTOL MYERS SQUIBB CO (US) 2007-07-25 CN disclosed
US-6617325-B1 Inhibitors of the microsomal triglyceride-transfer protein BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-09-09 US disclosed