Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006186 | 0.83 | KDM4E (0.35) | FFAR1KDM4EALDH1A1POLBGRM5 | |
| SCHEMBL1010354 | 0.80 | GRM5 (0.46) | KDM4EALDH1A1POLBSMOGRM5 | |
| SCHEMBL1008733 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1POLBGRM4GRM5 | |
| SCHEMBL1675489 | 0.76 | ADK (0.34) | KDM4EALDH1A1POLBABL1BCR | |
| SCHEMBL1006671 | 0.76 | HPGDS (0.41) | ALDH1A1POLBABL1BCRAR | |
| SCHEMBL1007852 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1POLBGRM5 | |
| SCHEMBL1008800 | 0.74 | RECQL (0.34) | ALDH1A1GRM5 | |
| SCHEMBL19063455 | 0.74 | ALDH1A1 (0.40) | KDM4EALDH1A1POLBEGLN1GRM5 | |
| SCHEMBL1527521 | 0.72 | MAPT (0.34) | ALDH1A1POLBAR | |
| SCHEMBL1007402 | 0.72 | S1PR3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512478-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084549-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-07-14 | — | — | WO | disclosed |