Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.66 |
| ▸ | MGLL | Q99685 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31011360 | 0.84 | FAAH (0.50) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL9584019 | 0.78 | FAAH (0.51) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL14877230 | 0.78 | FAAH (0.51) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL9584008 | 0.78 | FAAH (0.51) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL5306513 | 0.76 | FAAH (0.49) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL13134141 | 0.75 | — | — | |
| SCHEMBL21740366 | 0.74 | FAAH (0.44) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL18381526 | 0.74 | FAAH (0.48) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL3705963 | 0.74 | LMNA (0.54) | FAAHMGLLMAPTHTTSMN1; SMN2 | |
| SCHEMBL2571669 | 0.74 | LMNA (0.54) | FAAHMGLLMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-115873000-A | Isoquinolone and quinazolinone compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110023313-B | Bicyclic amide compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-110072863-B | RIP1 kinase inhibitors and methods of use | 豪夫迈·罗氏有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-109843886-B | Bicyclic pyridone lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-11110160-B2 | Glycoconjugation processes and compositions | PFIZER INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20200246448-A1 | GLYCOCONJUGATION PROCESSES AND COMPOSITIONS | PFIZER INC. | 2020-08-06 | — | — | US | disclosed |
| CN-110903255-A | Method for synthesizing 1,2, 4-triazole-3-formic acid | 上海东岳药业有限公司 | 2020-03-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11110160-B2 | Glycoconjugation processes and compositions | GNE, SIGLEC7, SIGLEC9 | FAAH 4540/4885MGLL 3354/4885MAPT 4003/4885 |
| US-20200246448-A1 | GLYCOCONJUGATION PROCESSES AND COMPOSITIONS | GNE, SIGLEC7, SIGLEC9 | FAAH 4540/4885MGLL 3354/4885MAPT 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.