SCHEMBL21740366

SCHEMBL21740366

CC(C)OC(=O)n1cncn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.44
MGLL Q99685 3/20 0.44
ATM Q13315 1/20 0.40
GPR119 Q8TDV5 1/20 0.36
PDE4B Q07343 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 4/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 2/20 0.35
PKM P14618 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
MITF O75030 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
HSP90AA1 P07900 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1414691 0.78
SCHEMBL22304265 0.74 FAAH (0.66) FAAHMGLLATMPDE4BMEN1
SCHEMBL26822942 0.74 ATM (0.42) FAAHMGLLATMPDE4BMEN1
SCHEMBL1167637 0.73 FAAH (0.44) FAAHMGLLATMGPR119PDE4B
SCHEMBL9427893 0.70
SCHEMBL8438655 0.69 LMNA (0.44) FAAHMGLLATMPDE4BMEN1
SCHEMBL7268279 0.69 ALDH1A1 (0.43) FAAHMGLLATMPDE4BMEN1
SCHEMBL23407929 0.69 NOS1 (0.44) PDE4BMAPTP2RX4
SCHEMBL31741537 0.69 FAAH (0.41) FAAHMGLLATMPDE4BMEN1
SCHEMBL31011360 0.68 FAAH (0.50) FAAHMGLLPDE4BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200054739-A1 CONJUGATED VACCINES SUTROVAX, INC. 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200054739-A1 CONJUGATED VACCINES ASNS, CD14, CD74 FAAH 3588/4885MGLL 2352/4885ATM 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.