Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304002 | 0.92 | DYRK1A (0.42) | TERTDYRK1AAPAF1CYP3A4TSHR | |
| SCHEMBL29888711 | 0.83 | CHRNB2 (0.42) | DYRK1ACHRNB2CHRNA4NPC1ALDH1A1 | |
| SCHEMBL927293 | 0.83 | CHRNB2 (0.42) | DYRK1ACHRNB2CHRNA4NPC1ALDH1A1 | |
| SCHEMBL30711473 | 0.80 | CHRNB2 (0.38) | DYRK1ATSHRCHRNB2CHRNA4NPC1 | |
| SCHEMBL12121725 | 0.76 | CHRNB2 (0.38) | DYRK1ACHRNB2CHRNA4NPC1ALDH1A1 | |
| SCHEMBL5084517 | 0.76 | CHRNB2 (0.38) | DYRK1ACHRNB2CHRNA4NPC1ALDH1A1 | |
| SCHEMBL30394548 | 0.76 | DYRK1A (0.42) | DYRK1ACHRNB2CHRNA4NPC1ALDH1A1 | |
| SCHEMBL1701025 | 0.76 | CHRNB2 (0.38) | DYRK1ATSHRCHRNB2CHRNA4NPC1 | |
| SCHEMBL941915 | 0.75 | CHRNB2 (0.48) | DYRK1ACHRNB2CHRNA4NPC1ALDH1A1 | |
| SCHEMBL12228885 | 0.74 | DYRK1A (0.38) | DYRK1ACHRNB2CHRNA4NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200246345-A1 | ALDEHYDE CONJUGATES AND USES THEREOF | ALDEYRA THERAPEUTICS, INC. | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200246345-A1 | ALDEHYDE CONJUGATES AND USES THEREOF | ALDH1A2, AOX1, ALDH2 | TERT 4020/4885DYRK1A 4123/4885APAF1 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.