Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | XPO1 | O14980 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22284505 | 0.80 | PKM (0.48) | PKMGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL28626528 | 0.80 | PKM (0.48) | PKMGAAKDM4EALDH1A1NPC1 | |
| SCHEMBL29174205 | 0.80 | TTR (0.43) | DPP4TTRCA12CA1CA2 | |
| SCHEMBL16863576 | 0.73 | GAA (0.52) | PKMGAAHPGDKDM4ECASP1 | |
| SCHEMBL29788898 | 0.73 | TTR (0.46) | DPP4TTRCA12CA1CA2 | |
| SCHEMBL5381056 | 0.72 | ALDH1A1 (0.42) | DPP4TTRCA12CA1CA2 | |
| SCHEMBL5381060 | 0.72 | ALDH1A1 (0.42) | DPP4TTRCA12CA1CA2 | |
| SCHEMBL29000262 | 0.72 | TTR (0.42) | DPP4TTRCA12CA1CA2 | |
| SCHEMBL26424371 | 0.72 | TTR (0.42) | DPP4TTRCA12CA1CA2 | |
| SCHEMBL30492201 | 0.71 | TTR (0.43) | DPP4TTRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700363-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-03-15 | — | — | CN | claimed |
| US-11680057-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-20 | — | — | US | claimed |
| US-12454523-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2025-10-28 | — | — | US | disclosed |
| CN-113412254-B | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-11-29 | — | — | CN | disclosed |
| US-12077525-B2 | Herbicidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-09-03 | — | — | US | disclosed |
| CN-118440059-A | Herbicidal mixtures | 先正达农作物保护股份公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-113423270-B | Herbicidal mixtures | 先正达农作物保护股份公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117700363-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117683024-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117658988-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20230301300-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-28 | — | — | US | disclosed |
| US-20230286954-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-14 | — | — | US | disclosed |
| EP-4195929-A1 | HERBICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| US-11680057-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-20 | — | — | US | disclosed |
| US-11680057-B2 | Pyrazole derivatives | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-20 | — | — | US | disclosed |
| CN-116157016-A | Herbicidal composition | 先正达农作物保护股份公司 | 2023-05-23 | — | — | CN | disclosed |
| US-11472792-B2 | Herbicidal mixtures | SYNGENTA CROP PROTECTION AG (CH) | 2022-10-18 | — | — | US | disclosed |
| CN-113423270-A | Herbicidal mixtures | 先正达农作物保护股份公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113412254-A | Pyrazole derivatives | 先正达农作物保护股份公司 | 2021-09-17 | — | — | CN | disclosed |
| US-20200245625-A1 | PYRAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286954-A1 | PYRAZOLE DERIVATIVES | RB1, NQO2, RBX1 | PKM 2095/4885DPP4 1556/4885TTR 4084/4885 |
| US-11680057-B2 | Pyrazole derivatives | RB1, NQO2, RBX1 | PKM 2095/4885DPP4 1556/4885TTR 4084/4885 |
| US-12454523-B2 | Pyrazole derivatives | RB1, NQO2, RBX1 | PKM 2095/4885DPP4 1556/4885TTR 4084/4885 |
| US-12077525-B2 | Herbicidal compounds | DDT, ACHE, CAT | PKM 791/4885DPP4 135/4885TTR 3986/4885 |
| US-20230301300-A1 | HERBICIDAL COMPOSITIONS | GMDS, DDT, AADAC | PKM 496/4885DPP4 114/4885TTR 4771/4885 |
| US-11472792-B2 | Herbicidal mixtures | DDT, CBR3, AS3MT | PKM 2791/4885DPP4 1331/4885TTR 4605/4885 |
| US-20200245625-A1 | PYRAZOLE DERIVATIVES | RB1, NQO2, RBX1 | PKM 2095/4885DPP4 1556/4885TTR 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.