Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311749 | 0.81 | SMN1; SMN2 (0.47) | TP53TSHRLMNAALDH1A1HTT | |
| SCHEMBL15155882 | 0.80 | ATM (0.55) | TP53TSHRLMNAALDH1A1PKM | |
| SCHEMBL28136856 | 0.80 | TP53 (0.53) | TP53TSHRLMNAALDH1A1PKM | |
| SCHEMBL23923878 | 0.80 | ALDH1A1 (0.53) | TP53TSHRLMNAALDH1A1PKM | |
| SCHEMBL4959484 | 0.80 | ATM (0.55) | TP53TSHRLMNAALDH1A1PKM | |
| SCHEMBL27331113 | 0.80 | TP53 (0.49) | TP53TSHRLMNAALDH1A1PKM | |
| SCHEMBL1008276 | 0.78 | MAPT (0.50) | TP53TSHRLMNAALDH1A1CES2 | |
| SCHEMBL2453170 | 0.76 | TP53 (0.49) | TP53TSHRLMNAALDH1A1PKM | |
| SCHEMBL4707186 | 0.76 | TRPM8 (0.60) | TP53TSHRLMNAALDH1A1PKM | |
| SCHEMBL2453168 | 0.76 | TP53 (0.49) | TP53TSHRLMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512478-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084549-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-07-14 | — | — | WO | disclosed |
| CN-102015651-A | Compounds and compositions as TLR activity modulators | IRM LLC | 2011-04-13 | — | — | CN | disclosed |