Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.55 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2752589 | 0.86 | LMNA (0.68) | MAPTMEN1STAT3KMT2AELOVL1 | |
| SCHEMBL21224359 | 0.84 | HDAC6 (0.64) | MAPTMEN1KMT2AELOVL1ADORA3 | |
| SCHEMBL21224358 | 0.84 | HDAC6 (0.64) | MAPTMEN1KMT2AELOVL1ADORA3 | |
| SCHEMBL22305385 | 0.84 | MAPT (0.54) | MAPTMEN1STAT3KMT2AELOVL1 | |
| SCHEMBL21224203 | 0.84 | XIAP (0.65) | MAPTMEN1STAT3KMT2AELOVL1 | |
| SCHEMBL10954503 | 0.84 | MAPT (0.61) | MAPTMEN1STAT3KMT2AELOVL1 | |
| SCHEMBL21224205 | 0.84 | XIAP (0.65) | MAPTMEN1STAT3KMT2AELOVL1 | |
| SCHEMBL10957280 | 0.84 | MAPT (0.61) | MAPTMEN1STAT3KMT2AELOVL1 | |
| SCHEMBL2754064 | 0.83 | ROCK2 (0.62) | MAPTMEN1STAT3KMT2AELOVL1 | |
| SCHEMBL21224175 | 0.83 | MEN1 (0.60) | MAPTMEN1STAT3KMT2AELOVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-04 | — | — | US | disclosed |
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138480-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | MAPT 2074/4885MEN1 1366/4885STAT3 3892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.