Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.48 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305493 | 0.90 | MAPT (0.47) | MAPTNPC1RAB9AALDH1A1HDAC3 | |
| SCHEMBL22305360 | 0.90 | SMN1; SMN2 (0.50) | MAPTELOVL1NPC1CASP3RAB9A | |
| SCHEMBL22290384 | 0.89 | KMT2A (0.48) | MAPTMAPK1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL22306234 | 0.89 | HDAC3 (0.52) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22305521 | 0.88 | ELOVL1 (0.43) | ELOVL1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL22290665 | 0.88 | PARP1 (0.45) | MAPTPARP1ALDH1A1HDAC4 | |
| SCHEMBL22306605 | 0.88 | HDAC3 (0.46) | MAPTNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL22305379 | 0.88 | ADORA3 (0.53) | MAPTNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL22290277 | 0.88 | ALDH1A1 (0.56) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL31173366 | 0.88 | ALDH1A1 (0.56) | MAPTNPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |