SCHEMBL2230609

SCHEMBL2230609

COc1ccccc1P(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA12 O43570 1/20 0.55
CA4 P22748 1/20 0.55
CA14 Q9ULX7 1/20 0.55
ALDH1A1 P00352 5/20 0.44
TP53 P04637 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.44
ADRA2B P18089 1/20 0.44
PTGS1 P23219 1/20 0.44
MAPK1 P28482 2/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ENPP2 Q13822 1/20 0.41
ORAI1 Q96D31 1/20 0.40
ORAI2 Q96SN7 1/20 0.40
ORAI3 Q9BRQ5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30837263 1.00 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL889796 0.86 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL50148 0.80 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL10414766 0.80 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL29405044 0.80 CA1 (0.60) CA1CA2CA7CA9CA12
SCHEMBL2154356 0.79 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL28888547 0.79 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL8419557 0.78 CA1 (0.57) CA1CA2CA7CA9CA12
Hydrochloric Acid SCHEMBL7972166 0.78 CA1 (0.57) CA1CA2CA7CA9CA12
SCHEMBL15658840 0.78 CA1 (0.57) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3853172-B1 METHODS FOR PREPARING ARYLPHOSPHINE-BORANE COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-05 EP claimed
US-20210380613-A1 METHODS FOR PREPARING ARYLPHOSPHINE-BORANE COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-12-09 US claimed
EP-3853172-A1 METHODS FOR PREPARING ARYLPHOSPHINE-BORANE COMPLEXES Dow Global Technologies LLC (US) 2021-07-28 EP claimed
WO-2020061151-A1 METHODS FOR PREPARING ARYLPHOSPHINE-BORANE COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2020-03-26 WO claimed
EP-1354886-B1 Process for the preparation of tertiary phosphines SALTIGO GMBH (DE) 2009-08-26 EP claimed
US-7230136-B2 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2007-06-12 US claimed
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
US-20030229240-A1 Reacting phosphorus halide with organomagnesium compound in presence of copper compound LANXESS DEUTSCHLAND GMBH (DE) 2003-12-11 US claimed
EP-1354886-A1 Process for the preparation of tertiary phosphines Bayer Aktiengesellschaft (DE) 2003-10-22 EP claimed
EP-3853172-B1 METHODS FOR PREPARING ARYLPHOSPHINE-BORANE COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-05 EP disclosed
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION L'OREAL (FR) 2023-06-01 US disclosed
EP-4171490-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION L'OREAL (FR) 2023-05-03 EP disclosed
WO-2022003040-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION L'OREAL (FR) 2022-01-06 WO disclosed
US-4952728-A OPTICALLY ACTIVE SOCIETE NATIONALE ELF AQUITAINE (FR) 1990-08-28 US disclosed
EP-0115945-B1 SYNTHESIS OF HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLES CELANESE CORPORATION (US) 1988-11-30 EP disclosed
US-4535144-A AMINOARYL ESTER REACTANT, TWO-STAGE MELT POLYMERIZATION CELANESE CORPORATION (US) 1985-08-13 US disclosed
US-4533725-A BY-PRODUCT INHIBITION; HEATING A FOAMED PREPOLYMER DELANESE CORPORATION (US) 1985-08-06 US disclosed
EP-0115945-A2 Synthesis of high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-08-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165771-A1 PROCESS FOR TREATING KERATIN FIBERS USING PARTICULAR AMINO ACIDS IN HIGH CONCENTRATION KRT18, CKAP4, VIM CA1 1100/4885CA2 1216/4885CA7 1308/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP CA1 311/4885CA2 223/4885CA7 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.