Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290407 | 0.87 | SMARCA2 (0.44) | AURKAROCK2BLMGRM5WDR5 | |
| SCHEMBL22290647 | 0.85 | PARP1 (0.47) | ROCK2ROCK1CYP3A4PRKACA | |
| SCHEMBL31173242 | 0.85 | PARP1 (0.47) | ROCK2ROCK1CYP3A4PRKACA | |
| SCHEMBL22290558 | 0.81 | BLM (0.46) | AURKAABL1BLMGRM5KMT2A | |
| SCHEMBL22306016 | 0.79 | SMARCA2 (0.43) | AURKAROCK2BLMGRM5WDR5 | |
| SCHEMBL25498927 | 0.78 | AURKA (0.41) | AURKAROCK2GRM5L3MBTL1ROCK1 | |
| SCHEMBL30316038 | 0.77 | SCN9A (0.45) | ABL1BLMIRAK4 | |
| SCHEMBL22306010 | 0.77 | SCN9A (0.45) | ABL1BLMIRAK4 | |
| SCHEMBL22306576 | 0.76 | ROCK1 (0.47) | ROCK2ROCK1CYP3A4PRKACAGSK3B | |
| SCHEMBL22305714 | 0.76 | WNT3A (0.45) | ABL1KMT2AROCK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |