SCHEMBL22306359

SCHEMBL22306359

N#CC(C#N)=CNCc1cccs1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.44
ALDH1A1 P00352 5/20 0.42
HPGD P15428 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
USP2 O75604 1/20 0.41
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 2/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5329090 0.74 TAAR1 (0.38) POLBALDH1A1HPGDL3MBTL1USP2
SCHEMBL22307309 0.72 KMT2A (0.38) POLBALDH1A1KDM4EKMT2AMEN1
SCHEMBL3937741 0.72 ADH1B (0.48) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL1258123 0.71
SCHEMBL1231251 0.71
SCHEMBL6008115 0.71
SCHEMBL20825028 0.71
SCHEMBL22306357 0.70 GAA (0.41) POLBALDH1A1KMT2AMEN1MAPT
SCHEMBL22306362 0.70 LMNA (0.43) POLBALDH1A1HPGDL3MBTL1USP2
SCHEMBL178423 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020156298-A1 APPLICATION OF MALONONITRILE COMPOUND AS BACTERICIDE 沈阳化工大学 2020-08-06 WO disclosed