SCHEMBL22307356

SCHEMBL22307356

c1ccc(CCc2ncc(-c3cccc(-c4cnc(CCc5ccccc5)[nH]4)c3)[nH]2)cc1

nearest known ligand 0.84

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 7/20 0.84
HPGDS O60760 3/20 0.59
BRS3 P32247 2/20 0.56
PADI1 Q9ULC6 1/20 0.52
PADI3 Q9ULW8 1/20 0.52
PADI4 Q9UM07 1/20 0.52
PADI2 Q9Y2J8 1/20 0.52
DAO P14920 1/20 0.51
MMP2 P08253 1/20 0.47
SCN2A Q99250 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1501842 0.92 PDE10A (1.00) PDE10AHPGDSBRS3DAOMMP2
SCHEMBL6650785 0.78 PDE10A (0.73) PDE10AHPGDSBRS3DAOMMP2
SCHEMBL2835802 0.75 HPGDS (1.00) PDE10AHPGDSBRS3
SCHEMBL1501948 0.75 PDE10A (0.70) PDE10AHPGDSBRS3SCN2A
SCHEMBL28770122 0.73 PDE10A (0.66) PDE10AHPGDSBRS3
SCHEMBL3719490 0.73 PDE10A (0.62) PDE10AHPGDSBRS3DAOMMP2
SCHEMBL13680963 0.71 PDE10A (0.64) PDE10AHPGDSBRS3SCN2A
SCHEMBL259049 0.70 PDE10A (0.64) PDE10AHPGDSSCN2A
SCHEMBL2562957 0.70 PDE10A (0.64) PDE10AHPGDSSCN2A
SCHEMBL1501900 0.70 PDE10A (0.64) PDE10AHPGDSSCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3875525-A1 MATERIAL FOR HOT MELT EXTRUSION SYSTEM, MODELING MATERIAL FOR 3D PRINTERS, METHOD FOR PRODUCING MODELING MATERIAL FOR 3D PRINTERS, AND THREE-DIMENSIONAL MODEL KONICA MINOLTA, INC. (JP) 2021-09-08 EP disclosed
WO-2020158647-A1 MATERIAL FOR HOT MELT EXTRUSION SYSTEM, MODELING MATERIAL FOR 3D PRINTERS, METHOD FOR PRODUCING MODELING MATERIAL FOR 3D PRINTERS, AND THREE-DIMENSIONAL MODEL コニカミノルタ株式会社 2020-08-06 WO disclosed