Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.62 |
| ▸ | DAO | P14920 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 5/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1501842 | 0.76 | PDE10A (1.00) | PDE10ADAOMMP2BRS3HPGDS | |
| SCHEMBL9938772 | 0.74 | MMP2 (0.71) | PDE10ADAOMMP2MMP9MMP13 | |
| SCHEMBL9938012 | 0.74 | PDE10A (0.57) | PDE10ADAOMMP2MMP9MMP13 | |
| SCHEMBL1196577 | 0.73 | CYP1A2 (0.43) | PDE10AAOC3TAAR1 | |
| SCHEMBL22307356 | 0.73 | PDE10A (0.84) | PDE10ADAOMMP2BRS3HPGDS | |
| SCHEMBL14486412 | 0.73 | DAO (1.00) | PDE10ADAOMMP2MMP9MMP13 | |
| SCHEMBL22361953 | 0.72 | — | — | |
| SCHEMBL3520010 | 0.69 | DAO (0.62) | PDE10ADAOMMP2MMP9MMP13 | |
| SCHEMBL3344549 | 0.69 | MEN1 (0.58) | PDE10ADAOMMP2MMP9MMP13 | |
| SCHEMBL23461156 | 0.68 | TAAR1 (0.49) | DAORAB9ANPC1TAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136438-A1 | (DIHYDRO) IMIDAZOISO (5, 1-A) QUINOLINES AS FSH RECEPTOR AGONISTS FOR THE TREATMENT OF FERTILITY DISORDERS | N.V. ORGANON (NL) | 2010-12-02 | — | — | WO | disclosed |