SCHEMBL22307392

SCHEMBL22307392

N#CC(C#N)=C(N)NCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.50
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47
GRIN2A Q12879 2/20 0.47
GRIN2B Q13224 2/20 0.47
GRIN2C Q14957 2/20 0.47
GRIN3A Q8TCU5 2/20 0.47
SIGMAR1 Q99720 2/20 0.47
ALOX12 P18054 2/20 0.47
HPGD P15428 2/20 0.47
ALDH1A1 P00352 1/20 0.47
PLIN1 O60240 1/20 0.46
LMNA P02545 1/20 0.46
PLIN5 Q00G26 1/20 0.46
ABHD5 Q8WTS1 1/20 0.46
GAA P10253 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11609036 0.80 KMT2A (0.50) SIGMAR1HPGDGAAKMT2APOLB
SCHEMBL22306421 0.78 HPGD (0.51) MCL1ALOX12HPGDALDH1A1PLIN1
SCHEMBL6729087 0.76 MCL1 (0.53) MCL1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11498666 0.76 MCL1 (0.53) MCL1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6729091 0.76 MCL1 (0.53) MCL1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL17814271 0.76 MCL1 (0.61) MCL1ALOX12HPGDALDH1A1PLIN1
SCHEMBL17763698 0.76 MCL1 (0.61) MCL1ALOX12HPGDALDH1A1PLIN1
SCHEMBL17763697 0.76 MCL1 (0.61) MCL1ALOX12HPGDALDH1A1PLIN1
SCHEMBL22307403 0.75 MCL1 (0.47) MCL1ALOX12HPGDALDH1A1PLIN1
SCHEMBL6187669 0.74 IDO1 (0.53) MCL1ALOX12HPGDALDH1A1PLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020156298-A1 APPLICATION OF MALONONITRILE COMPOUND AS BACTERICIDE 沈阳化工大学 2020-08-06 WO disclosed